By Trost B.M., Fleming I., Pattenden G. (eds.)
Quantity three covers carbon-to-carbon unmarried bond forming reactions concerning sp 3, sp 2 and sp carbon facilities, yet simply these which don't contain additions to C-X &pgr;-bonds. the quantity first compares and contrasts the alkylation reactions of all kinds of sp 3 carbon nucleophiles and likewise covers vinyl and alkynyl carbanions. Following on from quantity 2, a separate part covers Friedel-Crafts alkylation reactions, that is complemented by way of discussions of polyene cyclizations and electrophilic transannular cyclizations in synthesis. Coupling reactions resulting in &agr;-bond formation, and related to all kinds of mixtures of sp 3, sp 2 and sp carbon facilities are subsequent lined, together with these reactions according to pinacol, acyloin and phenol oxidative coupling reactions, and in addition the Kolbe response. Rearrangement reactions, resulting in carbon-to-carbon &agr;-bond formation, are usually utilized in a smart demeanour in synthesis. the amount contains all these rearrangement reactions in response to intermediate carbonium ions and carbanions, and in addition contains the benzil-benzilic acid and the Wolff rearrangements. the amount closes with assurance of carbonylation reactions, and using carbene insertion reactions into the C-H bond in synthesis.