By Hans Neurath (auth.), Kenneth A. Walsh (eds.)
Methods in Protein series research -1986 brings jointly studies of the newest method to be had to protein chemists for learning the molecular element of proteins. The papers during this quantity represent the complaints of the 6th foreign convention on equipment in Protein series research, which used to be held on the collage of Washington in Seattle, Washington on August 17-21, 1986. This sequence of meetings has taken position in the course of a interval whilst new suggestions in protein chemistry and molecular biology have enabled not just exploration of the keep watch over of protein functionality, but in addition deduction of the genetic starting place of proteins, and labo ratory new release of infrequent protein molecules for therapeu tic and advertisement use. the present experiences are considering the potential in which experimental questions could be spoke back instead of at the organic implications in particular structures. The scope of the assembly was once particularly extensive, empha sizing microanalytical concepts and the relative benefits of DNA sequencing, mass spectrometry and extra tradi tional degradation options. A spotlight of the assembly used to be the Qrowing wisdom of the function of mass spec trometry within the research of proteins. The complementarity of protein sequencing and DNA sequencing suggestions was once obvious during the discussions and a number of other papers handled the tactic of acquiring series in formation from small quantities of protein so that ap propriate oligonucleotide probes should be built and the encoding nucleic acids se. quenced and manipu lated.
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